Assessment of Psoriatic Skin Features Using Non-Invasive Imaging Technique

Background: Psoriasis is one of the most commonly recognized dermatological diseases, characterized by distinct structural changes, hyperproliferation and inflammation. The aim study was quantitative comparisons psoriatic skin with without lesions non-invasive imaging methods. Methods: 71 patients diagnosed psoriasis vulgaris underwent at site lesion such lesion. Skin density, epidermis thickness subepidermal low-echogenic band (SLEB) were measured high-resolution ultrasound (HFU). Blood perfusion assessed using laser speckle contrast analysis (LASCA) temperature thermal camera. Hyperspectral camera used to obtain spectral reflectance profiles in changes. Results: greatest differences density epidermal between unchanged observed on forearms. covered plaques 80% less dense, this area 121% thicker. SLEB knee (Me = 0.389 mm). a higher 33.6 vs. Me 31) blood than 98.76 50.65). shows lower from 623 nm 1000 nm; below value, reflectance. Conclusions: thickness, perfusion, can be useful parameters for monitoring course its treatment, especially since examination proposed methods non-invasive, easy perform clinical conditions.